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Leslie B. Smith; Frank Cohen; Ralph G. Nichols
JAMA. 1944;126(16):1027-1028. doi:10.1001/jama.1944.82850510003008b.
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Spontaneous leukocytic regeneration has been reported1 to occur in cases of agranulocytosis when the primary or secondary infections were controlled by specific chemotherapy (sulfonamide).

We believe that the reporting of 2 cases of agranulocytosis successfully treated with penicillin is timely. To date 1 such case has been cited;2 however, there have been none reported in detail.3


Case 1.—  A Negro aged 18 years was admitted to the Station Hospital, Camp Wolters, Texas, Feb. 28, 1944 complaining of sore throat, fever, cough and pain in his chest.The history revealed that he had had measles and mumps as a child and "malaria" eighteen months before admission without recurrence. Although he denied having had a penile lesion or other manifestations of syphilis, the syphilitic register revealed that the Kline test had twice been positive in November 1943, that the Kahn and Wassermann tests were positive in


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