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ARTICLE | November 9, 1929

AGRANULOCYTOSIS ASSOCIATED WITH ANAL ULCER

Robert W. Buck, M.D.

JAMA. 1929;93(19):1468-1469. doi:10.1001/jama.1929.27110190001011a.

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A considerable number of articles are available in regard to the subject of agranulocytosis; as these have been comprehensively reviewed in other recent papers,⁵ no attempt will be made in this report to summarize the literature.

The term agranulocytosis was first suggested in 1922 by Werner Schultz⁶ to designate a condition found by him in five cases showing febrile gangrenous angina involving the tonsils and neighboring tissues (one showing in addition a coincident gangrenous colpitis). These cases were all characterized by a marked leukopenia and almost complete disappearance of poly-morphonuclear leukocytes from the blood smear. The published case reports and the description of the disease and its manifestations do not include, so far as I have been able to determine, any examples of this condition occurring in association with primary ulcerative or gangrenous lesions in other parts of the alimentary canal than the throat. Secondary ulcerations have been

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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Buck RW. AGRANULOCYTOSIS ASSOCIATED WITH ANAL ULCER. JAMA. 1929;93(19):1468-1469. doi:10.1001/jama.1929.27110190001011a.

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