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October 5, 1929, Vol 93, No. 14 >
ARTICLE | October 5, 1929

LIPODYSTROPHIA PROGRESSIVA

J. B. Bilderback, M.D.
JAMA. 1929;93(14):1062-1063. doi:10.1001/jama.1929.27110140001009.
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To William Osler belongs the credit of first having observed and described a case of lipodystrophia. A girl, aged 10 years, came under his care in 1895. Five years earlier the child's face had started slowly and insidiously to lose the subcutaneous fat. Within a short time the upper extremities and trunk became involved.

The first case reported in medical literature was by Barraquer1 of Barcelona in 1906. However, the condition has existed for centuries.

Ameline and Quercy2 report a case occurring in an ancient ruler of Egypt in 1500 B. C. This was Pharaoh Amenophis IV, as deduced from mural tablets of ancient Egypt. The special feature of the disease—the loss of subcutaneous fat in the upper part of the body and the pronounced increase of fat deposits in the region below the crest of the ilium—are portrayed in the pictures of this ruler and have been

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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