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August 31, 1929, Vol 93, No. 9 >

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ARTICLE | August 31, 1929

Edema and Its Treatment.

JAMA. 1929;93(9):717. doi:10.1001/jama.1929.02710090057042.
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ABSTRACT

According to the author, edema results from a disturbance in the balance between the water intake and the rate of movement of the water from the tissues to the blood stream. The important factor is a diminution of the rate of water movement from the tissues. This slowing may result: (1) from an adaptation on the part of the entire mechanism for water exchange for the purpose of maintaining the constancy of the water part of the internal milieu, especially the constancy of the water content and the volume of the blood when this is threatened; (2) from a change in the intensity of function of the water-regulating center, and (3) in local edema, from a change in the local peripheral part of the mechanism for water exchange. This adaptation involves changes in the constellation of the electrolytes in the tissues through which the water passes. The author supports this

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