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JAMA. 1929;93(8):625-626. doi:10.1001/jama.1929.02710080051025.
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ABSTRACT

The Intradermoreaction of Typhoid  The intradermoreaction, which makes it possible to distinguish subjects immunized against the typhoid toxin from those who are receptive, has recently been exploited by MM. Dufourt, Arloing and Pujos (of Lyons), who have brought the results of their researches before the Academy of Medicine. They used cultures of typhoid bacilli in bouillon, heated for an hour at 58 C., then filtered, and the filtered cultures subjected to the lytic action of an effective bacteriophage. The facts that they report point to an evident analogy between the reaction that they were studying and the reactions of Schick and Dick in diphtheria and scarlet fever, respectively. The intradermoreaction in typhoid becomes positive by producing a redness of the skin, at the site of the inoculation, in subjects who have not had typhoid fever, and in subjects who have the disease or have recently become convalescent, and in persons

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