Handbuch der pathogenen Mikroorganismen.

The first article in this issue of the Handbuch is an excellent critical review of the existing literature on allergy and anaphylaxis. Indeed, its principal shortcoming is its extensiveness (about 250 pages). Without a detailed cross-index it is almost impossible to find minutiae. Hence, the monograph will be of value principally to experts in the field, who will wish to study the mature expressions of Professor Doerr, who has been a careful student of the phenomena of the hypersensitive state. His bibliography of approximately a thousand references is unusually complete. Doerr takes issue with Coca on the classification of hypersensitive phenomena, particularly because the latter's scheme does not logically include the allergies of infections (Invasionsallergien). This calls to mind the criticism, now often expressed, that perhaps a fundamental blunder was made some decades ago when hypersensitive phenomena came to be considered a group apart. Perhaps the failure to establish logically