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JAMA. 1944;125(7):496. doi:10.1001/jama.1944.02850250036013.
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SAFETY IN PRESCRIBING BY UNITS  Deaths have followed too frequently the erroneous use of potent therapeutic agents. On numerous occasions The Journal has reported and issued warnings about drugs improperly used or misleadingly labeled and packaged. Preparations intended for use by mouth can be expected to elicit unwanted reactions when injected. Other preparations available in two or more concentrations are likely to yield trouble unless due care is exercised when they are ordered, dispensed and applied. One cause of many accidents is the common practice of prescribing containers instead of units. Thus, the intern and nurse are instructed to give "one ampul" instead of a prescribed number of grams or milligrams expressed in percentage if the drug is in solution. N. N. R. accepted brands of the local anesthetic procaine hydrochloride, for example, include 0.02, 0.05, 0.07, 0.15 and 0.2 Gm. tablets and ampuls of 1, 2 and 10 per


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The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
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