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ARTICLE |

RECTAL ADMINISTRATION OF LIVER EXTRACT (COD)

PAUL REZNIKOFF, M.D.
JAMA. 1929;93(5):367-368. doi:10.1001/jama.1929.02710050021007.
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During the course of an investigation of the efficacy of liver extract derived from the cod,1 a patient was encountered who developed pneumonia and could not retain the medication when given by mouth. The results obtained when the extract was given by rectum were so striking and may have so much significance in the treatment of patients who are vomiting that the case is reported now.

REPORT OF CASE  Mrs. R. A. C., white, aged 58, was admitted to the ward, April 19, 1929, because of faintness and weakness of four days' duration. Her family and past histories do not have any bearing on her present illness, which dates from about four months before admission, when she had some teeth extracted on account of pyorrhea. She then had "indigestion" and a sense of being "filled up." She suffered from some dyspnea on exertion, occasional attacks of palpitation, and some

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