JAMA. 1929;93(3):191-193. doi:10.1001/jama.1929.02710030027011.
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The increasing importance of focal infections as etiologic factors in disease renders it necessary, from time to time, to take stock of current impressions and of their real significance. Possibly no one focus has received as much attention as have the teeth, and possibly no one focus has been so poorly investigated. The most comprehensive presentation of the topic from the etiologic standpoint is that of Greve1 who, writing in 1926, was able to gather a bibliography of thirty-nine numbers. Greve's theory of the formation of the granulomas is a combination of the various theories which had been advanced at different times previous to his publication by Partsch, Dependorf, Euler, Grawitz, Malassey and others. Briefly presented, his explanation is that in the gum there are many embryonal rests of epithelial cells left there in the course of development of the tooth germ. If in the neighborhood of such a


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