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CHRONIC LYMPHATIC LEUKEMIA IN TWIN BROTHERS AGED FIFTY-SIX

William Dameshek, M.D.; Harry Austryn Savitz, M.D.; Benjamin Arbor, M.D.
JAMA. 1929;92(16):1348-1349. doi:10.1001/jama.1929.92700420002009b.
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The occurrence of leukemia in twins has, so far as we know, never been reported. The appearance, almost simultaneously, of chronic lymphatic leukemia in identical twin brothers, aged 56, resulting in their deaths within a short time of each other, seemed to us a remarkable occurrence, and worth reporting. It brings up interesting speculations as to the etiology of chronic leukemia.

REPORT OF CASES 

Case 1.  —Jacob G., a Jewish cobbler, aged 56, was first seen by one of us (H. A. S.) for the Federated Jewish Charities of Boston. He was seen in consultation with another of us (W. D.) on March 14, 1928, at which time the patient said that he had been troubled with enlarged glands for almost two years. The family history was not significant, except that he said a twin brother was suffering from a similar condition. The patient had been married thirty-three years; his wife

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