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April 20, 1929, Vol 92, No. 16 >
ARTICLE | April 20, 1929

SOLUTION OF PITUITARY AND RUPTURED UTERUS

A. M. MENDENHALL, M.D.
JAMA. 1929;92(16):1341-1346. doi:10.1001/jama.1929.02700420025008.
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The oxytocic properties of the posterior lobe of the pituitary gland were first described by Dale1 in 1907. Almost from the first announcement there has been a steady increase in its use. Many different pharmaceutic companies are now manufacturing it under various names. It has been found to be a valuable time saver for the accoucheur and has rendered the use of the obstetric forceps much more infrequent. It often enables the obstetric attendant who is without obstetric forceps, or without the skill to use them, to complete the delivery of his patient. Somewhat like the discovery of ergot, it was hailed as a wonderful aid to the obstetrician.

It was not long, however, after its use was begun until words of warning were sounded. Careful investigators began to report unfavorable effects on both the mother and the child. Some of these were intracranial hemorrhage and asphyxia of the

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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BMJ 2010;341:c5893-c1494.
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