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Kenneth B. Raper, Ph.D.; Robert D. Coghill, Ph.D.
JAMA. 1943;123(17):1135. doi:10.1001/jama.1943.02840520051020.
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To the Editor:—  Since July 1941 the Northern Regional Research Laboratory, which is one of four regional research laboratories operated by the Bureau of Agricultural and Industrial Chemistry, Agricultural Research Administration, U. S. Department of Agriculture, has been extensively engaged in research on the production of penicillin. This work has been broad in scope, including the isolation of many new penicillin producing organisms, spore selection to secure higher producing strains, improvement of the culture mediums and isolation and purification of the penicillin itself.During recent weeks a number of scientific articles and press releases have appeared indicating that the production of penicillin preparations suitable for external use is a comparatively simple matter that can be undertaken in laboratories possessing only limited facilities, or even in the kitchen. The work thus reported, in some cases, may constitute noteworthy contributions to the field of penicillin therapy, and it is not our wish


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