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RIO DE JANEIRO

JAMA. 1929;92(14):1200-1201. doi:10.1001/jama.1929.02700400058024.
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ABSTRACT

Antidysenteric Vaccine  Dr. Eduardo Vaz read a paper some time ago in which he claimed that he had obtained perfect results with antidysenteric vaccine as an immunizing agent when it was given by mouth. In his second paper he relates his attempts to make the vaccine more active, and describes his experiments on shortening the time necessary to prepare it in large quantities. Dr. Vaz did not succeed in substituting the original medium for a more economical one or in reducing the time of culture, without altering the immunizing value. He established several important circumstances, however, in the technic of the preparation. He had more success with the vaccine in broth than in peptonated water, and with the vaccine made from a bacterial culture of three weeks than with that whose cultures were of less time (two, four, seven, ten and fourteen days). The preparations in the least dilutions (experiments

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