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April 6, 1929, Vol 92, No. 14 >
ARTICLE | April 6, 1929

GRADENIGO'S SYNDROME

Garnett Cheney, M.D.
JAMA. 1929;92(14):1180. doi:10.1001/jama.1929.92700400001012.
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Gradenigo's syndrome consists of a triad of symptoms which were first described by Gradenigo in 1904. They are acute suppurative otitis media, severe temporoparietal pain, and a paresis or paralysis of the abducens nerve on the same side. The syndrome has been frequently reported abroad, and recently several articles on the subject have appeared in this country, but these have been almost entirely confined to the special journals on otology and ophthalmology. The clinical picture is of general interest, as the pain is in the form of a trigeminal neuralgia, except that it is limited to the first division of the fifth nerve and may persist for weeks or months after the discharge from the ear has ceased. It is also important to recognize the ocular palsy, which usually occurs between the fourth and sixth weeks, as a part of the same picture, and to know that

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