The voluminous literature on biology and its related sciences from 1914 to 1929 has been evaluated by Handovsky in an attempt to outline briefly the chief points of view and the chief methods of attack of problems that have characterized pharmacology during this period. In the introduction he discusses what is properly the domain of pharmacology. The first and longest chapter deals with all aspects of metabolism, including the mechanism of intracellular oxidations and the pharmacology of heat regulation and oxygen transport. Other chapters similarly treat the colloidal structure of the cell, water and salt metabolism and, more briefly, new developments in the older pharmacology of the central and peripheral nervous systems, skeletal muscle, digestive tract, and glands of internal secretion. The text cites more than 1,600 references, which are collected at the end of the volume. Unfortunately, they are not arranged alphabetically. There is also an index.