R. G. HOSKINS, Ph.D., M.D.
JAMA. 1931;97(10):682-685. doi:10.1001/jama.1931.02730100006003.
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Schizophrenia, representing, as it does, a distortion of the whole personality, offers a problem that is essentially coextensive with that of human psychology. Since the patient shows more or less characteristic deviations in his functional activities, the problem is also nearly coextensive with that of human physiology. To whatever extent specific pathology may prove to play a part in the psychosis, that field of knowledge, too, is involved. It is obvious, therefore, that any attempt to deal productively with the problem literally "as a whole" would be chimerical. The ineptitude of any such attempt is further indicated by the fact that no major problem in medicine has ever been solved in that way. To the practical investigator the actual problem presented is primarily one of strategy—of selecting an angle of approach that offers most promise of significant returns for the labor involved. He must deal individually with workable portions of


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