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March 9, 1929, Vol 92, No. 10 >
ARTICLE | March 9, 1929

ACUTE OSTEOMYELITIS

DEAN LEWIS, M.D.
JAMA. 1929;92(10):783-786. doi:10.1001/jama.1929.02700360021006.
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ABSTRACT

Acute pyogenic osteomyelitis has been termed a pyemia occurring during the period of growth in which the inflammatory changes in the bones predominate in the clinical picture. While there may be a question as to whether the term general infection should be applied to processes in which bacteria are not found in the blood from time to time, or increase in it, there can be no question as to the hematogenous origin of the disease and its close relation to general pyogenic infections with metastases. It should be remembered in this connection that staphylococci seem to use the blood as a means of transport and that they not infrequently disappear from it, to be delivered into it again at some other time.

Accumulating clinical and bacteriologic experiences indicate that the clinical course of the disease varies considerably with different organisms. Lannelongue and Achard, in 1890, made the first communication relative

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