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Simon Flexner, M.D.
JAMA. 1928;91(25):2014-2015. doi:10.1001/jama.1928.02700250078036.
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To the Editor:  —I noticed in The Journal, November 10, an inquiry about the preparation and preservation of convalescent poliomyelitis serum. As you may receive other inquiries of the same kind, I am sending you a copy of the directions we are issuing for its collection and preservation.In selecting convalescent donors for the preparation of serum, account is taken of their general physical condition, age and body weight. The amount of blood taken is determined by these factors. From healthy children of 13 to 16, the amount drawn varies between 300 and 500 cc. From adults 500 to 1,000 cc. may be taken if necessary, and in the case of professional donors this amount may be removed once in three weeks if their condition allows. It is customary to pay the professional donors $10 for 100 cc. drawn. Probably the more recent the attack of poliomyelitis, the more efficient


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