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MALIGNANT MELANOMA OF THE CHOROID WITH EXTENSIVE METASTASIS TREATED BY REMOVING SECRETING TISSUE OF THE TESTICLES

William P. Herbst, M.D.
JAMA. 1943;122(9):597. doi:10.1001/jama.1943.72840260002007a.
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A. K., a man aged 69, had a malignant melanoma of the choroid removed on Sept. 29, 1939 by Dr. J. B. Griffith. The pathologic report of the specimen, which was submitted to Lieut. Col. J. E. Ash, M. C., United States Army, curator of the Army Medical Museum, follows:

"Gross: The eye has been opened in the horizontal plane. The retina is detached, and behind it on one side is a pale mass measuring 16 by 9 mm., which extends from the optic disk to a point midway between the equator and the ciliary body.

"Microscopic: Extending from the ora serrata almost to the optic disk is a tumor mass which appears to be breaking through Bruch's membrane in several places. A few thin walled blood vessels are seen; pigment is not discernible. The cells are spindle shaped with oval nuclei, round or polygonal with abundant cytoplasm and smaller

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