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THE CLINICAL PREVENTION AND DIAGNOSIS OF LIVER DYSFUNCTION

SIDNEY A. PORTIS, M.D.
JAMA. 1943;121(10):733-736. doi:10.1001/jama.1943.02840100019005.
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Liver disease and liver dysfunction are becoming increasingly prevalent. It is now known that any chronically deficient diet may lead eventually to liver disease.

The American dietary is reported deficient in the vitamin B complex. One might assume that the recent enthusiasm for the intake of concentrated vitamin preparations might have counteracted this. However, two factors have nullified to a large extent the possible beneficial effect of increased vitamin intake: 1. Concentrated vitamin preparations are relatively expensive, and those who can afford to take them get an adequate amount in their diet, anyway. 2. A large proportion of commercial preparations do not contain the whole vitamin B complex—are apt to be rich in thiamine and nicotinic acid but poor in the other factors. There is some evidence to show that this disproportion can do harm as well as good. The desire for "sylphlike" figures has undoubtedly induced lowering of the

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