—H. C., a girl, aged 11, was admitted to my clinic, Sept. 12, 1926, in diabetic coma. The family and past history were unimportant. The present illness began two weeks before admittance, at which time the child's mother noticed that she suddenly began to drink large amounts of water and to have a craving appetite. This was soon followed by loss of weight, lassitude and irritability, and two days before admission she began to get drowsy and could not get out of bed on account of weakness. The family physician was called the next day and referred her to the clinic.The child was in deep coma and appeared emaciated. Her breathing was of the Kussmaul type and there was a heavy odor of acetone. The temperature was 99 F.; the pulse, 125. The eyeballs were very soft and the mucous membranes of the mouth and throat dry.