An extensive review of the literature will not be attempted here as this phase of the subject has been admirably discussed in the two reports of Minot and Murphy1 dealing with the treatment of pernicious anemia by dietary means. In the Johns Hopkins Hospital clinic, liver diet was first used almost two years ago. During this time, twenty-four undoubted cases of pernicious anemia have been treated, nineteen by the liver diet and five by liver extract.
We have attempted to arrange the diet in the exact manner described by Minot and Murphy2 in their original paper. The only departure made, particularly applying to our later patients, was an increase in the rather low fat constituent to make the diet more palatable. From a practical standpoint, it would seem that the most important reason for having the fat content very low is to keep milk products of the diet