Joslin, not many years ago, joyfully exclaimed, "Insulin is here." Similarly, today we may proclaim the glad tidings that "the anti-pernicious anemia body has been found." In some respects the latter discovery is the greater of the two. It had long been supposed that the pancreas made and contained an active antidiabetic hormone. Banting's great contribution lay in the discovery of the method of its extraction. Minot and his collaborators, however, have not only shown how a specific anti-pernicious anemia body may be isolated from the liver but have been largely responsible for the idea that this organ contains such a substance as well.
It has been our privilege, since Dr. Minot first told us of the discovery, to observe the effect first of the Minot-Murphy1 diet, and later of the Cohn-Minot2 liver extract, in quite a large series of patients with pernicious anemia in the wards of