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THE ADRENAL MEDULLA

J. M. ROGOFF, M.D.
JAMA. 1935;104(23):2088-2092. doi:10.1001/jama.1935.92760230009010a.
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Note.  —This article and the articles in the previous issues of The Journal are part of aseries published under the auspices of the Council on Pharmacy and Chemistry. Other articles will appear in succeeding issues. When completed, the series will be published in book form.—Ed.Glandular therapy is based chiefly on the capacity of hormones or other products, obtained from endocrine glands, to substitute for deficiency or absence of function of those organs in the body. Although the adrenal medulla has been studied extensively, both experimentally and clinically, its function has not been explained satisfactorily. Yet its hormone, epinephrine, is one of the most commonly used drugs in the practice of medicine and surgery. The present purpose, therefore, can best be accomplished by discussing available physiologic and pharmacologic information in the light of or with special emphasis on its therapeutic application. In view of the vast literature on

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