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October 10, 1942, Vol 120, No. 6 >

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ARTICLE | October 10, 1942

INTERMITTENT HYPOTHERMIA WITH DISABLING HYPERHIDROSIS

Arthur M. Hoffman, M.D.; Frederick W. Pobirs, M.D.
JAMA. 1942;120(6):445-447. doi:10.1001/jama.1942.82830410001008.
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In 1934 Hines and Bannick1 described a clinical entity of recurrent hypothermia associated with disabling sweating. It is the only case reported in the literature to date. In 1935 we were privileged to observe a patient with apparently the identical condition. We have studied him during approximately yearly attacks since that date and feel that the observations on this prolonged study and treatment are worth recording as the second instance in the literature.

The patient of Hines and Bannick, a man aged 22, was hospitalized because of intermittent attacks of sweating, chills and subnormal temperature. He had had these attacks for ten years. They would begin each year in December or January and would continue for from four to six weeks. "At the onset of each attack there had been a period of nausea and vomiting of from five to seven days; following this gastric upset the usual cycles

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