JAMA. 1928;90(26):2099-2100. doi:10.1001/jama.1928.02690530027010.
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The great value of cholecystography as an aid in the diagnosis of gallbladder disease has been demonstrated by a large number of favorable reports during the past four years. The limitations of the test have been studied to some extent, principally by Graham,1 the originator of the method, who warns us to be cautious about interpreting slight variations in the filling and emptying of the gallbladder as evidence of disease. He believes that cholecystography is a means of studying the functional activity of the gallbladder rather than a method which depicts either a normal condition or one of disease. His warning against overenthusiasm for the test is warranted, because errors in interpretation may easily occur as a result of incomplete knowledge of the function and mechanism of the gallbladder. The inaccessibility of the region for the application of the roentgen ray may also contribute to errors of interpretation, particularly


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