The first edition of this book, which has been written for students and practitioners of medicine, was reviewed in these pages a little over a year ago and its possible usefulness described by the statements "It is inclusive, up to date, sufficiently exhaustive for ordinary textbook purposes and extremely readable. Many of Jackson's fine tracings and colored diagrams are borrowed to enrich its pages. The bibliographic references are numerous and evince the author's wide acquaintance with the literature of his subject." While there has been no radical change in the plan of the second edition, the author has brought the information up to date and has removed a number of criticisms directed toward the first edition. The author's cognizance of late developments is attested by reference to U. S. P. XII, N. F. VII, heparin, "coumarin compound," gramicidin, tyrocidine, penicillin, pectin, blood and blood substitutes and the newer sulfonamides. This