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Robert M. Entwisle, M.D.; Joseph A. Hepp, M.D.
JAMA. 1935;104(5):395-396. doi:10.1001/jama.1935.92760050005010b.
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This case is made a matter of record for the reason that it is the second reported case in which the pituitary gland in a male shows the characteristic biologic and histologic changes identical with those found in the pituitary of pregnant women.

W. E., a white man, aged 22, a student, was perfectly well until two and one-half months before entering St. Francis Hospital, Pittsburgh, or until four months before his death. The onset was about two months after a large shepherd dog playfully pawed him, causing some pain in the left side of the scrotum. The day following this there was some swelling in the scrotum and he consulted a physician concerning it. Within a week the swelling and pain had entirely disappeared, and from that time on the testicle gave him no concern, nor did he in any way connect this with his illness until it was brought out by


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