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Die Aetiologie der bösartigen Geschwülste nach dem gegenwärtigen Stande der klinischen Erfahrung und der experimentellen Forschung.

JAMA. 1928;90(20):1656-1657. doi:10.1001/jama.1928.02690470062038.
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In textbooks of about 1900-1915, little space was devoted to the etiology of tumors. Discussions were mainly theoretical and of such phases of the subject as Cohnheim's conception of embryonal remnants, Hansemann's cell anaplasia, and Ribbert's explanation of the origin of carcinoma. Tumors of animals other than man or tumors in plants were not mentioned, and experimental investigations of tumors had just begun. Such an extensive review as this with its more than a thousand references to the literature and devoted altogether to the cause of tumors is certainly auspicious. One conclusion from its perusal is that the cancer problem is well along on the road to final solution The book presents what has been accomplished by the experimental study of tumors. Since the change of normal cells to rapidly growing cells of malignant tumors is not due to purely morphologic metamorphosis, there are scarcely any details of histology or


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