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May 16, 1942, Vol 119, No. 3 >
ARTICLE | May 16, 1942

TOXIC EFFECTS OF FUADIN AND ANTIMONY AND POTASSIUM TARTRATE

F. Gordon Cawston, M.D. (Cantab.)
JAMA. 1942;119(3):287. doi:10.1001/jama.1942.02830200055023.
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ABSTRACT

To the Editor:—  In the South African Medical Journal, Nov. 8, 1941, page 440, E. Ross Marshall of New York is reported to have said, in comparing antimony and potassium tartrate with fuadin (J. Nat. M. A.33:105 [May] 1941) that "fuadin is the better drug since it is less toxic.... As it is much less toxic, almost no untoward symptoms are noted from its use." Similar statements have been made in regard to the use of antimony in the treatment of leprosy.No thoughtful reader can think that a 6 per cent solution is as "toxic" as a powder containing from 36 to 39 per cent of the same drug, and an equivalent amount of the two solutions reveals that the solution of antimony and potassium tartrate is free of the undesirable effects of the pyrocatechol compounds.Estimates of cure are difficult in instances in which extensive parasitic

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