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Ralph H. Major, M.D.
JAMA. 1928;90(11):846. doi:10.1001/jama.1928.92690380002012a.
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In the case of Charcot's foot reported here, the picture presented by the patient's feet, as shown in figure 1, was very striking. At first glance it suggested a developmental anomaly or the condition of feet that have been treated to some mutilating process, such as the classic foot binding in China. The patient's statement that he formerly wore number 10 shoes but now wore nothing larger than a 6 added at first to this confusion of the disease picture. A careful history with the results of the examination made clear, however, what the condition really was.

In 1910, the patient, then aged 46, weighed 350 pounds (159 Kg.) and wore number 10 shoes. He was at that time employed in an occupation that kept him on his feet a great deal, and calluses appeared on the soles of both feet. Following these calluses, an abrasion appeared on


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