While performing a series of experiments involving ligation and resection of the vas deferens, I became interested in the physiology of the storage of spermatozoa and of their progress from the testis to the urethra. Experiments were devised to elucidate obscure points that seemed to be interesting. Some of these experiments and the conclusions drawn from them are herewith presented.
In some species of animals there are cyclic periods of testicular activity. This is especially noticeable in those animals that hibernate. But in many species, and this is true in man, there is a continuous production of spermatozoa. The spermatozoa are present in great numbers in the lumen of the seminiferous tubules. The quantity produced per unit of time varies considerably according to physiologic conditions. Attention has been called to this fact elsewhere,1 and it need not be discussed here.
Not all maturing germ cells become spermatozoa. Some of