0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

HETEROTOPIC INTESTINAL MUCOSA AS A POSSIBLE FACTOR IN THE GENESIS OF GASTRIC ULCER

JAMA. 1934;103(18):1380-1381. doi:10.1001/jama.1934.02750440040015.
Text Size: A A A
Published online

The occurrence of heterotopic intestinal mucosa in the mucous membrane of diseased stomachs has been known for some time. It has been found in cases of chronic gastritis, carcinoma, achylia and pernicious anemia. Most observers regard it as an instance of metaplasia arising on a basis of an inflammatory process. This theory found its support in the fact that heterotopic islands of intestinal mucosa occurred with greatest frequency in chronic atrophic gastritis and only rarely in normal stomachs. According to this view, defects in the gastric mucosa resulting from an inflammatory process permit the growth of a new and indifferent epithelium, which may later differentiate into the type resembling intestinal epithelium. The regeneration is therefore of a faulty, atypical kind rather than a true metaplasia. Moszkowitz1 in fact designated it as "indirect metaplasia." This view was shared by Lubarsch, Faber, Heyrovsky and, more recently, by Puhl, Stoerck, Konetzny and

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Letters

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();