0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

THE TREATMENT OF MUSCULAR DYSTROPHY WITH GLYCINE

JAMA. 1934;103(16):1236-1237. doi:10.1001/jama.1934.02750420048012.
Text Size: A A A
Published online

The idea of treating muscular dystrophy by the administration of glycine resulted directly from chemical analysis of the urine. The fact that the method is not yet definitely established as clinically successful in the present form of application does not detract from the essential importance of the fundamental observations. Creatinuria has been noted in many diseases that primarily or secondarily attack the muscular system. This led Thomas and his co-workers to investigate the effect of prolonged administration of glycine on the clinical course of progressive muscular dystrophies. In their preliminary report it was stated that the ingestion of from 15 to 20 Gm. of glycine daily raised the creatinuria of different cases by different degrees, depending on the extent of the original creatinuria. After some weeks the creatinurias were found to decrease despite the continuance of glycine. Coincident with the decrease in the creatinuria there was a rise in the

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Letters

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();