JAMA. 1928;90(7):507-508. doi:10.1001/jama.1928.02690340009004.
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The etiology of endometriosis has caused more speculation during the past few years than any other gynecologic condition. The origin of these heterotopic growths of endometrium becomes more important each day as an increasing number of reports reveal that they are quite a common lesion in the female pelvis and occur usually during the reproductive age.

Sampson1 recently reported observations based on 257 cases occurring in his private practice during the past four years. This author2 states that evidence of misplaced endometrial tissue can be demonstrated in from 10 to 20 per cent of women between the age of 30 years and the menopause who come for the operative relief of gynecologic conditions.

The most widely accepted theory is that advanced by Sampson3 of the regurgitation of tubal and uterine epithelium through the fallopian tubes into the free pelvic cavity. He was able to demonstrate4 these


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