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Comment & Response |

Composition of the Sepsis Definitions Task Force—Reply

Clifford S. Deutschman, MD, MS1; Mervyn Singer, MD, FRCP2
[+] Author Affiliations
1Center for Pediatric Research, Steven and Alexandra Cohen Children’s Medical Center, New Hyde Park, New York
2Bloomsbury Institute of Intensive Care Medicine, University College London, London, United Kingdom
JAMA. 2016;316(4):461-462. doi:10.1001/jama.2016.6395.
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In Reply The letters from Dr Shrestha, Drs Wira and Swenson, and Drs Burnham and Roman raise valid and important critiques about a process that is inherently complex and imperfect.

We, the 2 co-chairs, determined the composition of the Sepsis Definitions task force after first being appointed by the Society of Critical Care Medicine and the European Society of Intensive Care Medicine. We invited 15 highly published individuals with broad knowledge over a wide range of sepsis-related topics and 2 members who drove the massive data analyses needed to develop the new clinical criteria. Several other individuals, including a leading female scientist, were invited but were otherwise committed. We recognize that our solitary focus on expertise resulted in a task force that lacked diversity. We sincerely regret this result and hope that future efforts will result in broader representation.


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July 26, 2016
Charles R. Wira III, MD; Kai E. Swenson, MD
1Department of Emergency Medicine, Yale School of Medicine, New Haven, Connecticut
2Department of Internal Medicine, Stanford University School of Medicine, Stanford, California
JAMA. 2016;316(4):460. doi:10.1001/jama.2016.6371.
July 26, 2016
Ellen L. Burnham, MD; Jesse Roman, MD
1Department of Medicine, University of Colorado School of Medicine, Aurora
2Department of Medicine, University of Louisville Health Sciences Center, Louisville, Kentucky
JAMA. 2016;316(4):460-461. doi:10.1001/jama.2016.6383.
July 26, 2016
Gentle S. Shrestha, MD, FCCP
1Department of Anesthesiology, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal
JAMA. 2016;316(4):459-460. doi:10.1001/jama.2016.6386.
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