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ARTICLE |

Moderne Biologie.—Moderne Medizin.

JAMA. 1931;96(14):1172. doi:10.1001/jama.1931.02720400070039.
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ABSTRACT

This brochure defends the unorthodox thesis that nonspecific immunization is much more important than specific immunization; that, indeed, recovery from infectious diseases as well as natural immunity are due to the nonspecific reaction. Specific immunity is developed only as a secondary result of the nonspecific reaction in a limited number of diseases, such as the exanthems, mumps and pertussis; and it protects rather than cures. The further fact that in the immunization mechanism the cells are so much more important than the fluids of the body explains the failure of serotherapy to fulfil the high expectations with which it was launched. The author advances arguments to prove that even diphtheria antiserum is protective rather than curative. Were it curative, why should it fail when given at the height of the disease? To use colon and streptococcus and many other supposedly specific vaccines in those diseases whose etiologic agents do not

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