In bacterial endocarditis, sinus thrombosis, the septicemias and other similar conditions, methods of blood culture easy to apply are satisfactory to a gratifying degree. In certain of the acute infections such as typhoid, pneumonia, and epidemic meningitis the causative organism can be recovered from the blood stream early in the infection in a high percentage of cases. In the latter group, however, it is rarely necessary to obtain a culture from the blood to establish diagnosis. When obtained, it is more rarely of benefit in the treatment of disease.
The importance of blood cultures is being constantly reemphasized by the persistent attempts to cultivate organisms from the blood in the rheumatic and arthritic conditions. Some observers have apparently succeeded, but others, no doubt equally careful in their technic, have failed to corroborate them. Confidence that the causative agent of rheumatic fever or some of the forms of arthritis can be