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H. O. McPheeters, M.D.
JAMA. 1931;96(14):1139-1140. doi:10.1001/jama.1931.27220400002011a.
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The injection treatment of varicose veins has passed the experimental stages and is now accepted as a standard mode of therapy for this condition. So much has been written on the history of this method of treating varicose veins that further repetition is needless. Suffice it to say that it has had many and just criticisms and though perfection has not been attained, yet the dangers and complications associated with the treatment can now be avoided and today it is the safest method for the treatment of varicose veins and their many complications.

The theory of the treatment is based on three factors:

  1. The flow of blood in varicose veins is slowed or reversed.

  2. By the injection of various chemical solutions into the lumen of the vein a reaction is brought about on the intimal lining of the vein wall.

  3. The injected solution causes a change in the blood constituents


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