These are the concluding volumes in a new system of the therapeutics of internal disease. They cover such topics as the endocrine glands, the vitamins and allergy, which are, of course, centers of medical interest at this time. Since the contributors are men of repute in the subjects they discuss, the material may be considered adequate to the time of its preparation. Thus it must be recognized that already the advance in some of its fields is considerable if only the last three to six months are considered. Nevertheless the quality and scope of this work make it exceedingly practical as an office and hospital reference, particularly when the physician is confronted with the innumerable situations when something must be done and done promptly to meet a medical condition. Thus one finds in the article on hypertension only the most casual reference to recent studies with extracts of kidney.