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Comment & Response |

Noninvasive Ventilation and Outcomes Among Immunocompromised Patients

Jean-Pierre Frat, MD1; Rémi Coudroy, MD1; Arnaud W. Thille, MD, PhD1
[+] Author Affiliations
1CHU de Poitiers, Medical Intensive Care Unit, Poitiers, France
JAMA. 2016;315(17):1901-1902. doi:10.1001/jama.2016.0674.
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To the Editor The use of noninvasive ventilation as first-line therapy for immunocompromised patients with acute respiratory failure remains controversial.1,2 Dr Lemiale and colleagues3 reported the largest randomized clinical trial to date (374 immunocompromised patients) with the aim of assessing whether noninvasive ventilation could improve outcomes. No difference was found between patients treated with oxygen therapy alone or with noninvasive ventilation.


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May 3, 2016
Virginie Lemiale, MD; Djamel Mokart, MD; Elie Azoulay, MD, PhD; Groupe de Recherche en Réanimation Respiratoire Onco-Hématologique (GRRR-OH)
1Saint-Louis University Hospital, Paris, France
2IPC, Lyon, France
JAMA. 2016;315(17):1902-1903. doi:10.1001/jama.2016.0692.
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