0
ARTICLE |

The Periodicity and Cause of Cancer, Leukæmia and Allied Tumours with Chapters on Their Treatment

JAMA. 1941;117(16):1399. doi:10.1001/jama.1941.02820420091038.
Text Size: A A A
Published online

ABSTRACT

The author, a well known radiologist, has long been interested in the study of the growth rate of human cancer. The fact that malignant tumors have periods in which they grow rapidly, often though not invariably followed by a latent stage, has been known by clinicians for many years. Pathologists have long noted that the number of mitotic figures, for example, varies enormously from time to time, as determined by multiple biopsies on the same neoplasm. The rhythms of growth noted in grafted animal tumors are dependent more on the nutritional arrangements between the animal host and the tumor and the rise and fall of tissue immunity, owing to the fact that a graft is to a certain extent, even though growing, a foreign material, so that this observation made by Bashford many years ago is not of great interest. When selected stocks homozygous for the tumor inoculated are employed,

Topics

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
/>
First page PDF preview

Figures

Tables

References

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();