William R. Klingensmith, M.D.
JAMA. 1934;102(26):2182-2183. doi:10.1001/jama.1934.62750260005009f.
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Camphor poisoning is uncommon. Cases with a fatal termination have been reported.1 Recovery following the ingestion of 450 grains (30 Gm.), and death from the ingestion of 18 grains (1.2 Gm.) is reported. Benz,2 Haft,3 Blair1 and Cottrell4 report recovery after the ingestion of varying amounts of camphor in oil. Osborne5 says: "It is difficult to cause poisoning in the human unless the amount is excessive, then respiratory depression and convulsions might be caused." Stevens6 says: "Toxic doses first produce excitement, nausea and vomiting, delirium and epileptiform convulsions, then coma and collapse." Neither text states that the outcome may be fatal. Recovery without sequelae or complications seems to be the rule; however, in Cottrell's4 case very definite evidence of cerebral irritation continued for several days. Of the later reports in the literature, camphor in oil is universally the preparation ingested. The earlier


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