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JAMA Clinical Guidelines Synopsis |

Management of Atopic Dermatitis

Sarah L. Stein, MD1; Adam S. Cifu, MD2
[+] Author Affiliations
1Section of Dermatology, University of Chicago, Chicago, Illinois
2Section of General Medicine, University of Chicago, Chicago, Illinois
JAMA. 2016;315(14):1510-1511. doi:10.1001/jama.2016.1459.
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This JAMA Clinical Guidelines Synopsis summarizes the American Academy of Dermatology’s 2014 guideline on management of atopic dermatitis.

Box Section Ref ID

Guideline title Guidelines of Care for the Management of Atopic Dermatitis: Management and Treatment of Atopic Dermatitis With Topical Therapies

Developer American Academy of Dermatology (AAD)

Release date May 7, 2014

Prior version 2004

Target population Pediatric and adult patients with atopic dermatitis (AD) of all severities

Major recommendations

  • Application of nonpharmacologic moisturizers is an integral component of the management of patients with AD, resulting in reduced disease severity and a decrease in use of pharmacologic interventions (level of evidence I).

  • Topical corticosteroids (TCSs) are an appropriate treatment of AD not controlled by moisturizers (level of evidence I).

  • Topical calcineurin inhibitors (TCIs) are an important class of topical medication allowing for steroid-sparing interventions after achieving initial disease control with TCSs (level of evidence I). The data suggest that proactive regular, intermittent use of TCIs is additionally effective in maintaining disease remission (level of evidence I).

  • Evidence suggests that bleach baths and intranasal mupirocin can decrease disease severity in those with moderate to severe AD and clinical signs of secondary bacterial infection (level of evidence II).

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