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Robert D. Barnard, M.D.
JAMA. 1941;117(14):1203. doi:10.1001/jama.1941.02820400061022.
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To the Editor:—  In a communication to The Journal (Aug. 10, 1940, p. 475) commenting on my report of a patient whose blood showed a series of positive reactions for syphilis following successful vaccination for variola (Illinois M. J.77:78 [Jan.] 1940) Drs. A. P. Bay and M. I. Sankstone stated that I had attributed this effect to vaccinia. I am sorry that this imputation should have been drawn from my report, which merely recorded the observations. It is not proper to draw conclusions from the report of a single case of this type. Nor can the conclusions of Drs. Bay and Sankstone that because they had examined 100 serologically negative persons both before and after vaccinia inoculation with negative results be held to minimize the importance of this type of vaccination as a source of error in the presumptive blood serologic reactions for syphilis.Considering what has been


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