0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

THE APPLIED PHYSIOLOGY OF BILE SECRETION AND BILE SALT THERAPY

A. C. IVY, Ph.D., M.D.
JAMA. 1941;117(14):1151-1154. doi:10.1001/jama.1941.02820400009003.
Text Size: A A A
Published online

Numerous questions arise in the mind of the clinician and physiologist regarding the regulation of bile salt output and the rational therapeutic use of bile salts in hepatic and biliary tract disease. My associates and I have sought to answer some of these questions by studies on animals, since patients with a total bile fistula are scarce and none have been available to us. In addition, there are certain questions which cannot be answered by clinical observation.

FOOD  It has been clearly established that protein stimulates the formation of bile and bile salt production.1 The situation with regard to fat and sugar is not so clear. There is no evidence showing that fat and sugar increase bile salt production; the available evidence is to the contrary. When sugar is given to a fasting biliary fistula animal that is receiving no bile salts enterally, cholic acid and bile volume output

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Letters

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();