Study concept and design: Tew, Herman, Clarke.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: Hua, Carvalho, Herman, Clarke.
Critical revision of the manuscript for important intellectual content: Tew, Huang, Herman, Clarke.
Statistical analysis: Hua, Carvalho, Tew.
Administrative, technical, or material support: Tew, Huang.
Study supervision: Herman, Clarke.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Herman reports receiving personal fees from Merck Sharp & Dohme, Lexicon Pharmaceuticals, and Profil Institute for Clinical Research. No other disclosures were reported.
Funding/ Support: This research was partly supported by grants 5R01 DK090435-02, P30 DK092949, and K24 DK105340 from the National Institutes of Health and grants 1028335 and 1079621 from the National Health and Medical Research Council.
Role of the Funder/Sponsor: The sponsors had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.