Our total series of cases of malignant diseases of the thyroid gland possibly includes 210 cases. Of these, however, ten cases have been classified as precancerous by the pathologists, and thirty-four are classified either as suspicious or as questionable, or have been under observation for too short a period to be included in this discussion. This report, therefore, is based on the observations in 166 cases of. malignant disease of the thyroid gland in which the diagnosis is not questioned. All these patients have lived more than one year since the diagnosis was made, or are dead; in those cases in which a microscopic examination of the growth has not been made, the clinical course has been typical of malignant disease.
Of the 10,355 cases in our total series of cases of diseases of the thyroid gland in which operation or some other form of treatment has been carried out,