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JAMA Clinical Guidelines Synopsis |

Screening for Gonorrhea, Chlamydia, and Hepatitis B

Audrey Tanksley, MD1; Adam S. Cifu, MD1
[+] Author Affiliations
1University of Chicago, Chicago, Illinois
JAMA. 2016;315(12):1278-1279. doi:10.1001/jama.2016.0223.
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Published online


This JAMA Clinical Guidelines Synopsis summarizes the US Preventive Services Task Force’s 2014 guidelines on screening for gonorrhea, chlamydia, and hepatitis B.

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Guideline titles Screening for Hepatitis B Virus Infection in Nonpregnant Adolescents and Adults: US Preventive Services Task Force Recommendation Statement; Screening for Chlamydia and Gonorrhea: US Preventive Services Task Force Recommendation Statement

Developer US Preventive Services Task Force (USPSTF)

Release dates September 23, 2014; May 27, 2014

Prior versions 2004 (hepatitis B), 2005 (gonorrhea), 2007 (chlamydia)

Funding source Agency for Healthcare Research and Quality (AHRQ)

Target population Hepatitis B: asymptomatic nonpregnant adolescents and adults; gonorrhea and chlamydia: all sexually active adolescents and adults

Major recommendations

  • Hepatitis B: All individuals at high risk of hepatitis B infection should be screened with hepatitis B surface antigen, surface antibody, and core antibody. High-risk populations include people born in high-prevalence areas (>2%), US-born unvaccinated infants whose parents are from high-prevalence areas, patients with human immunodeficiency virus infection, injection drug users, men who have sex with men, and household contacts of hepatitis B–infected persons (B recommendation).

  • Gonorrhea and chlamydia: All sexually active women aged 24 years or younger and older women at high risk of gonorrhea and chlamydia infection should be screened with a nucleic acid amplification test. Risk factors include new or multiple sex partners, inconsistent condom use in people not in monogamous relationships, previous or concurrent sexually transmitted infection (STI), and exchanging sex for money (B recommendation). There is insufficient evidence to assess the balance of benefits and harms of screening in men.

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The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
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