We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Comment & Response |

Preeclampsia and Congenital Heart Defects—Reply

Nathalie Auger, MD, MSc, FRCPC1; William D. Fraser, MD, MSc, FRCSC2; Laura Arbour, MD, MSc, FRCPC, FCCMG3
[+] Author Affiliations
1Institut national de santé publique du Québec, Montreal, Canada
2Department of Obstetrics and Gynecology, CRCHUS, University of Sherbrooke, Sherbrooke, Canada
3Department of Medical Genetics, University of British Columbia, Vancouver, Canada
JAMA. 2016;315(11):1168-1169. doi:10.1001/jama.2015.19084.
Text Size: A A A
Published online


In Reply Dr Brodwell and colleagues express concern that our analysis included infants born preterm and was possibly biased by heart defects related not to preeclampsia but rather to increased surveillance. The premise is that heart defects are more likely to be misdiagnosed in infants born preterm, as the heart is challenging to visualize or has yet to be fully formed at early gestational ages. Because many women with preeclampsia cannot deliver at term, they posit that the analysis should be restricted to critical heart defects, a group unlikely to be overdiagnosed.


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview




March 15, 2016
Kristoffer Brodwall, MD; Gottfried Greve, MD, DrMed; Nina Øyen, MD, MPH, DrMed
1Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway
2Department of Clinical Science, University of Bergen, Bergen, Norway
JAMA. 2016;315(11):1167-1168. doi:10.1001/jama.2015.19075.
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...